1. What unexpected similarity is revealed by the Conserved Domain search?
 

2. What does “pfam” tell you about the alpha crystallin domain? 50 or fewer carefully chosen, specific, precise and well-organized words!
 
 
 
 
 
 

3. What does “pfam” tell you about the unexpected domain and its function? 50 or fewer carefully chosen, specific, precise and well-organized words!
 
 
 
 

4. What is the hypothesized evolutionary and functional relationship between the crystalline domain and the unexpected domain? 50 or fewer carefully chosen, specific, precise and well-organized words!
 
 
 
 
 

5. Search PubMed to find one reference for a free review paper with additional information on this relationship. Cut and Paste the reference:
 

6. How many BLAST hits are there all together?

7. How many of the hits are from humans?

8. How many of the hits are from the common house mouse?

9. How many hits are there from the cow?

10. What is the Accession Number of the sixth hit? What organism is it from?

11. How many amino acids are in this protein?

12. How many of these amino acids align with the alpha crystallin from humans?

13. How many of these amino acids are identical to those in the human alpha crystalline?

14. What is the symbol for human alpha crystallin as given in the Gene database?

15. How many exons are found in the human alpha crystallin gene?

16. What is the RefSeq Accesion Number for the mRNA of the human alpha crystallin gene?

17. What is the RefSeq Accesion Number for the human alpha crystallin protein?

18. What is the locus of the human alpha crystallin gene?