POSTER
ACTIVITY (50 minutes)
FYI -You can use the protein databases, references (both images and information), to obtain any missing data on your protein and genetic disease:
Part 1 of your presentation activity (done in class on day 4) Find the amino acid sequence for the protein involved with the phenotype, condition or disease you have chosen. Then locate the PDB file containing the structural coordinates. Save this file to the desktop and open in Swiss-PDBviewer (make sure to send a copy to yourself and know how to download Swiss-PDBviewer on another computer). Part 2 of your presentation activity Use Swiss-PDBviewer to identify the defective site of your protein of interest and if possible the mutant protein. (Using separate coordinates or making changes within the wildtype protein structure). Save these images for your presentaion.
Examine and compile all relevant information. Print all information which you think may be useful for your Poster, and save it for later use. Hand in
a copy to your instructor!
* NOTE:
An explanation is not a simple statement of fact! An explanation
discusses how and why! An explanation is not simply a paraphrase
or a quote from a reference! It reflects your own understanding!
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