Common MRI sequences

T1 Weighted Imaging
T1 Weighted Imaging (T1)

T2 weighted imaging

T2 Weighted Imaging (T2)

T1 with Fat Saturation

T1 with Fat Saturation (T1 fat-sat)

T2 with Fat Saturation

T2 with Fat Saturation (T2 fat-sat)

Fluid Suppression (FLAIR)

Fluid Suppression (FLAIR)

Diffusion Weighted Imaging (DWI)

Diffusion Weighted Imaging (DWI

Susceptibility weighted imaging (SWI)

Susceptibility Weighted Imaging (SWI)

Proton Density

Proton Density

T1 with IV Gadolinium Contrast (T1-post)

T1 with IV Gadolinium Contrast (T1-post)

 

  • Notice that the same tissue type (muscle, fat, abdominal organs, brain tissue, bone etc.) look different on different sequences
  • Each sequence is designed to highlight different tissue types or different diseases
  • There are over 100 different MRI sequences
  • The simplest and most commonly used sequences are T1 and T2

 


Tissue representation in T1 and T2 weighted images

 

Fluid represented in a T1 and T2 weighted image

T1 and T2 representing fluid

T1: Dark

T2: Bright

Fat represented in a T1 and T2 weighted image

T1 and T2 representing fat

T1: Bright

T2: Dark

Muscle represented in a T1 and T2 weighted image.

T1 and T2 weighted image representing muscle

T1: Isointense

T2: Isointens

White matter represented in a T1 and T2 weighted image

T1 and T2 weighted image representing whitematter

T1: Isointense

T2: Isointense

Signal intensity (brightness) is often described as relative signal intensity. For example:

  • On T1 weighted images, white matter is hyperintense (brighter) compared to gray matter
  • On T2 weighted images, white matter is hypointense (darker) compared to gray mate